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Tumour cell delivery of antisense oligonuclceotides by human serum albumin nanoparticles

✍ Scribed by Heidrun Wartlick; Birgit Spänkuch-Schmitt; Klaus Strebhardt; Jörg Kreuter; Klaus Langer

Book ID
113690528
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
498 KB
Volume
96
Category
Article
ISSN
0168-3659

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Nanoparticles represent a promising tool for targeted drug delivery to tumour cells and are able to protect drugs against degradation. In our present study we developed targeted nanoparticles loaded with antisense oligonucleotides (ASOs) against Plk1 (polo-like kinase 1) prepared by heat denaturatio