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Tumour associated mutants of p53 can inhibit transcriptional activity of p53 without heterooligomerization

✍ Scribed by Jõers, A; Kristjuhan, A; Kadaja, L; Maimets, T

Book ID
110061622
Publisher
Nature Publishing Group
Year
1998
Tongue
English
Weight
404 KB
Volume
17
Category
Article
ISSN
0950-9232

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## Abstract The dominant oncogenic properties of mutant p53 have been recognized as a phenomenon associated with tumor progression a long time ago, even before it was realized that the major function of wild type p53 is that of a tumor suppressor. Recent advances in this fascinating area in tumor c