We have examined the effect of various cell monolayers on the ability of mouse spleen cells to lyse tumor cell targets (natural cytotoxicity reaction). Natural killer (NK) cell activity was reduced by as much as 75% depending on the cell substrate, with the greatest protection afforded by endothelia
Tumors skew endothelial cells to disrupt NK cell, T-cell and macrophage functions
✍ Scribed by Jennifer K. Mulligan; Deanne M. R. Lathers; M. Rita I. Young
- Publisher
- Springer-Verlag
- Year
- 2007
- Tongue
- English
- Weight
- 713 KB
- Volume
- 57
- Category
- Article
- ISSN
- 0340-7004
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