Highly regarded as the most comprehensive and authoritative work available, Tumors in Domestic Animals is an essential reference for veterinary pathologists, oncologists, clinicians, residents and students concerned with veterinary oncology. The fourth edition of this highly acclaimed textbook was updated and expanded by leading authorities on animal tumor pathology. The revision condenses a vast body of new research into useful information.
This definitive text addresses all aspects of veterinary tumor pathology in common domestic mammals. The user-friendly chapters are systems-based and each includes sections on relevant clinical pathology, immunohistochemistry and an extensive bibliography. Readers can easily locate salient clinical information, prevalence data, biological behavior, and accurate information about gross and microscopic lesions to help establish an accurate morphological diagnosis.
- Substantial text changes, including added clinical information.
- Hundreds of excellent images to aid in identification.
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Contributions by distinguished veterinary pathologists from both sides of the Atlantic.
This useful volume will undoubtedly be sought again and again as the ultimate reference on the pathology of tumors in domestic animals.
Doody Review Services
**Reviewer:**Keith L. Bailey, DVM, PhD, DACVP(University of Illinois College of Veterinary Medicine)
**Description:**This long awaited fourth edition of a cornerstone in veterinary pathology builds on all the prior editions. The previous edition was published in 1990 and during the 12 intervening years, veterinary pathology has experienced an unparalleled expansion with regard to the molecular aspects of tumorigenesis. Corresponding to this new understanding of the molecular events in oncology has been the development of diagnostic procedures and classification schemes to better categorize neoplasms and provide additional insight into their biologic behavior. The primary contribution of the editor of this edition and his esteemed panel of contributing authors is the manner in which this newly gained information is addressed. More specifically, the authors have made a special effort to include ancillary tests such as immunohistochemistry and to integrate clinical pathology data into many of the chapters. This edition contains 15 chapters, with an opening chapter that covers the molecular basis of cancer, and an appendix containing algorithms for tumor classification schemes. All of the chapters, as well as the appendix, contain current references.
**Purpose:**Not unlike the previous editions of this book, the editor and contributing authors have attempted to provide an overall picture of specific tumors in veterinary pathology, including sections on the clinical aspects and prevalence, gross features, microscopic lesions, and their biologic behavior. Particular attention is paid to the integration of molecular techniques such as immunohistochemistry and clinical pathology data book. Another important feature is the appendix, which contains classification schemes for common tumors in dogs and cats. The authors' objectives are clearly met and this edition will continue to maintain its position as a cornerstone in veterinary pathology.
**Audience:**Although the book primarily targets veterinary pathologists and veterinary pathology residents in training, it would be a useful reference for veterinary practitioners and veterinary students since it discusses the clinical relevance of specific tumors, including their biologic behavior. The list of contributing authors has been expanded from the previous edition, with most of the individuals widely recognized as having subspecialty interests in the field of veterinary pathology.
**Features:**The book provides relevant information about common (as well as somewhat obscure) neoplasms in domestic animal species. The 15 chapters are based on tumors in specific organ systems, with an opening chapter that provides an overview of the molecular basis of tumorigenesis, classification of tumors, and concepts in cancer management. One of the most important contributions of this edition is the integration of the molecular aspects of neoplasia (including molecular markers) into the book and an attempt to integrate clinical pathology data into each chapter. A feature which most readers will find useful is the appendix that provides classification schemes and algorithms for commonly encountered neoplasms in dogs and cats, including canine cutaneous mast cell tumors, canine soft tissue sarcomas, canine cutaneous hemangiosarcomas, canine cutaneous melanomas, feline irideal melanomas, canine urinary bladder carcinomas, canine splenic sarcomas, canine and feline mammary neoplasms, canine and feline lymphomas, canine and feline lung tumors, and canine and feline nasal tumors. Current references are provided with each category of tumor. Although many of the photographs are the same as the previous edition, there are several new photos; all illustrations are black and white. The editor does mention that color images are available on CD-ROM. The major shortcoming of the book is the price, effectively limiting its availability to diagnostic, research, and academic pathologists. Within each chapter, several fonts are used to subdivide the text, which may be visually disruptive to some readers.
**Assessment:**The fourth edition of this book has been eagerly awaited by veterinary pathologists and pathology residents. The significance of this edition to the field of veterinary pathology rivals the previous editions, which have long been considered cornerstones in the field. The editor of this edition maintains the standards set forth by the editor of the previous editions, and adds notable contributions related to the molecular aspects of tumor development, the usefulness of diagnostic markers, and the biologic behavior of the most commonly encountered tumors in domestic animal species. There is expanded coverage pertaining to the clinical relevance of the tumors, highlighting the need for interdisciplinary collaboration among veterinary pathologists, veterinary oncologists, and practitioners. Although many of the algorithms for commonly encountered neoplasms in dogs and cats provided in the appendix are sure to change over the next few years as in-depth prospective studies by veterinary oncologists are reported, they do serve as an outline for tumor grading at the present time. Many of the references in the appendix are within the past 3-4 years.