## Wild -type P16ICDKNZ MTSI) cDNA, directed by the cytomegalovirus (CMV) immediate early promoter, was transfected into RT4 and RTI I 2 bladder-carcinoma cell lines bearing a mutated endogenous P16ICDKNZ gene and lacking endogenous P 16lCDKN2 respectively. In both cases, only transfected clones w
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Tumorigenicity of human induced pluripotent stem cells depends on the balance of gene expression between p21 and p53
โ Scribed by Hisashi Moriguchi; Raymond T. Chung; Chifumi Sato
- Publisher
- John Wiley and Sons
- Year
- 2010
- Tongue
- English
- Weight
- 79 KB
- Volume
- 51
- Category
- Article
- ISSN
- 0270-9139
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The novel human pre-B cell line OZ was established from a patient with an aggressive form of non-Hodgkin's lymphoma. Karyotypic analysis of both the primary tumour and OZ cells revealed several marker chromosomes, including the t(14;18)(q32;q21) translocation, which involves the Bcl-2 gene, and alte