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Tumorigenesis as a consequence of genetic instability in Brca1 mutant mice

โœ Scribed by Chu-Xia Deng

Book ID
114070385
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
216 KB
Volume
477
Category
Article
ISSN
0027-5107

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## Abstract Mice with disrupted germline __p53__ alleles have been engineered by us and others and have been shown to have enhanced susceptibility to spontaneous tumors of various types. We monitored a large number of __p53__โ€deficient mice(__p53__+/โˆ’ and __p53__โˆ’/โˆ’) and their wildโ€type littermates