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Tumorhemmende β-Aminoketone

✍ Scribed by Wolfgang Meindl; Reiner Laske; Miroslava Böhm

Publisher
John Wiley and Sons
Year
1987
Tongue
English
Weight
312 KB
Volume
320
Category
Article
ISSN
0365-6233

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✦ Synopsis

Synthese der Verbindungen 1-9 und Testung auf Aktivitat an der P388D, Tumorzellinie werden beschrieben. Stark wirksam sind die P-Aminoketone 2-4, 7 und 9, die in der a-Stellung eine zusatzliche Aminomethylgruppierung besitzen.

Tumor Inhibiting P-Aminoketones

Synthesis of the compounds 1-9 and testing for activity against the P388Dl tumor celline are described. The p-aminoketones 2-4, 7 and 9, which bear an additional aminomethyl group in a-position. are strongly active.

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