Tumoral calcium pyrophosphate dihydrate deposition disease: Cytopathologic findings on fine-needle aspiration

✍ Scribed by Elizabeth A. Allen; Syed Z. Ali; Yener S. Erozan

• Publisher: John Wiley and Sons
• Year: 1996
• Tongue: English
• Weight: 582 KB
• Volume: 15
• Category: Article
• ISSN: 8755-1039
• DOI: 10.1002/(sici)1097-0339(199611)15:4<349::aid-dc20>3.0.co;2-n

✦ Synopsis

Tumoral calcium pyrophosphate dihydrate deposition disease (CPPD) is a rare non-neoplastic entity which mimics primary or metastatic soft-tissue or skeletal malignancy. Fewer than a dozen cases have been reported in the literature with only histologic descriptions. We present cytologicfindings of a unique case of CPPD in a 73-year-old black female with a history of end-stage renal disease. A fine-needle aspiration (FNA) was done on a 4 x 4-cm neck mass which was clinically thought to be malignant. Cytopathologic examination showed numerous macrophages with markedly dis

tended cytoplasm and containing multiple yellowish-orange, short rhomboid crystals. These were smngly bircfrigent on polarized microscopy, consistent with CPPD crystals. Diagn Cytopathol 1996;15:349-351. 0 19%Wiky-Liss.hc.