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Tumor suppressor U19/EAF2 regulates thrombospondin-1 expression via p53

✍ Scribed by Su, F; Pascal, L E; Xiao, W; Wang, Z


Book ID
109971115
Publisher
Nature Publishing Group
Year
2009
Tongue
English
Weight
790 KB
Volume
29
Category
Article
ISSN
0950-9232

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## Abstract Tumor suppressor p53 is an essential regulator in mammalian cellular responses to DNA damage including cell cycle arrest and apoptosis. Our study with Chinese hamster ovary CHO‐K1 cells indicates that when p53 expression and its transactivation capacity was inhibited by siRNA, UVC‐induc