Tumor suppressor genes
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Arnold J. Levine
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Article
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1990
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John Wiley and Sons
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English
โ 852 KB
## Abstract The retinoblastoma sensitivity protein (Rb) and the p53 gene product both appear to function as negative regulators of cell division or abnormal cellular growth in some differentiated cell types. Several types of cancers have been shown to be derived from cells that have extensively mut