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Tumor-promoting phorbol diesters inhibit in vitro antibody synthesis

✍ Scribed by Castagna, M.; Yagello, M.; Rabourdin-Combe, C.; Fridman, W.H.

Book ID: 122706823
Publisher: Elsevier Science
Year: 1980
Tongue: English
Weight: 475 KB
Volume: 8
Category: Article
ISSN: 0304-3835
DOI: 10.1016/0304-3835(80)90154-8

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## Abstract Phytohemagglutinin (PHA) or either of its isolectins, erythroagglutinin or leukoagglutinin, causes a dose‐dependent decrease in 12‐__O__‐tetradecanoylphorbol 13‐acetate (TPA)‐promoted transformation of Syrian hamster embryo cells, but has no effect on transformation induced by ultraviol