Tumor-promoting compounds from euphorbia cooperi di- and triesters of 16-hydroxy-12-desoxy-phorbol.

✍ Scribed by M. Gschwendt; E. Hecker

• Book ID: 104248631
• Publisher: Elsevier Science
• Year: 1970
• Tongue: French
• Weight: 199 KB
• Volume: 11
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(01)97771-8

✦ Synopsis

By a combination of liquid-liquid extraction methods with adsorption *+) chromatography from later of Euphorbia cooperi two new irritant and tumor promoting compounds C (I), C' (II) have been isolated. The mass spectra of C (M+516) and C' (~+558) show that they are di-and triesters respectively of the same parent alcohol (III: mw = 364). Further, the fragmentations M+ -88 and M+ -loo in the diester C and M+ -60. M' -88 and M+ -loo in the triester C' indicate that in both compounds the estergroupsmay