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Tumor progression in aberrant karyotypic human embryonic stem cells derived from long term suboptimal culture

✍ Scribed by Yang, Sheng; Lin, Ge; Lu, Guangxiu


Book ID
109846764
Publisher
Nature Publishing Group
Year
2008
Tongue
English
Weight
236 KB
Volume
18
Category
Article
ISSN
0007-0610

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## Abstract Human embryonic stem cells (hESCs) during long‐term culture acquire chromosomal changes similar to those occurring in tumorigenesis. This was raised concerns about the progression from hESCs to malignant cells. This study aimed to investigate the changes in chromosomes, cell phenotype,