After presensitization with IV hematoporphyrin derivative (HpD). neoplasms in the tracheobronchial tree of 18 patients were treated by photodynamic therapy (PDT) with 630-nm light from a tunable dye argon laser system delivered through quartz fibers passed through the biopsy channel of a flexible br
Tumor oxygen tension during photodynamic therapy
β Scribed by B.J. Tromberg; S. Kimel; A. Orenstein; S.J. Barker; J. Hyatt; J.S. Nelson; W.G. Roberts; M.W. Berns
- Publisher
- Elsevier Science
- Year
- 1990
- Tongue
- English
- Weight
- 450 KB
- Volume
- 5
- Category
- Article
- ISSN
- 1011-1344
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The exact mechanism by which photodynamic therapy (PDT) causes tumor destruction has not been elucidated. Early reports indicated that PDT causes direct cellular effects probably mediated by unstable oxygen species, resulting in cellular oxidation and death. More recently, PDT effects on tumor blood
## Abstract ## Background and Objectives Photodynamic therapy (PDT) efficacy appears to be enhanced in the presence of an intact immune system and PDT has been shown to augment antiβtumor immunity. The mechanisms leading to the enhancement of the host immune response to tumor are unclear. Antiβtum