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Tumor necrosis factor-α regulates in vivo expression of the rat UCP family differentially

✍ Scribed by Takayuki Masaki; Hironobu Yoshimatsu; Seiichi Chiba; Shuji Hidaka; Daisuke Tajima; Tetsuya Kakuma; Mamoru Kurokawa; Toshiie Sakata


Book ID
117049811
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
403 KB
Volume
1436
Category
Article
ISSN
1388-1981

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Anti-tumor necrosis factor ␣ (TNF-␣) treatment decreases nitric oxide (NO) synthesis and ameliorates the hyperdynamic circulation in portal hypertensive rats. We have recently demonstrated that nitric oxide synthase isoform 3 (NOS3) is overexpressed in portal hypertensive gastric mucosa and that res