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Tumor Necrosis Factor-α Plays a Central Role in Interleukin-2-Induced Pulmonary Vascular Leak and Lymphocyte Accumulation

✍ Scribed by Steven M. Dubinett; Min Huang; Alan Lichtenstein; William H. McBride; Jianyi Wang; Gerald Markovitz; David Kelley; Wayne W. Grody; Leah E. Mintz; Shawkat Dhanani

Book ID: 112239052
Publisher: Elsevier Science
Year: 1994
Tongue: English
Weight: 895 KB
Volume: 157
Category: Article
ISSN: 0008-8749
DOI: 10.1006/cimm.1994.1214

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## Abstract ## Objective To examine the role of interferon regulatory factor 1 (IRF‐1) in tumor necrosis factor α (TNFα)–induced interleukin‐18 binding protein a (IL‐18BPa) expression in rheumatoid arthritis synovial fibroblasts (RASFs). ## Methods TNFα‐induced IRF‐1 expression was assessed by r