Perturbation of hepatocyte growth regulation is associated with a number of liver diseases such as fibrosis and cancer. These diseases are mediated by a network of growth factors and cytokines that regulate the induction of hepatocyte proliferation and apoptosis. In this study, we have investigated
✦ LIBER ✦
Tumor-Necrosis Factor-α Modulates Mitogen-Activated Protein Kinase Activity of Epidermal-Growth-Factor-Stimulated MCF-7 Breast Cancer Cells
✍ Scribed by Nathalie Flury; Urs Eppenberger; Heinz Mueller
- Book ID
- 115132488
- Publisher
- John Wiley and Sons
- Year
- 1997
- Tongue
- English
- Weight
- 729 KB
- Volume
- 249
- Category
- Article
- ISSN
- 1432-1327
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## Abstract 1α,25‐Dihydroxyvitamin D~3~ [1α,25(OH)~2~D~3~], the hormonally active form of vitamin D~3~, has been shown to be a potent negative growth regulator of breast cancer cells both in vitro and in vivo. 1α,25(OH)~2~D~3~ acts through two different mechanisms. In addition to regulating gene tr