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Tumor necrosis factor-α increases chemokine gene expression and production in synovial fibroblasts from human temporomandibular joint

✍ Scribed by Naomi Ogura; Makiko Tobe; Hiroyuki Sakamaki; Hideaki Nagura; Yoshimitsu Abiko; Toshirou Kondoh

Book ID: 111254831
Publisher: John Wiley and Sons
Year: 2005
Tongue: English
Weight: 148 KB
Volume: 34
Category: Article
ISSN: 0904-2512
DOI: 10.1111/j.1600-0714.2005.00302.x

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## Abstract ## Objective To investigate the roles of MAPKs and NF‐κB in tumor necrosis factor α (TNFα)–induced expression of vascular cell adhesion molecule 1 (VCAM‐1) in human rheumatoid arthritis synovial fibroblasts (RASFs). ## Methods Human RASFs were isolated from synovial tissue obtained f