Neuronal death in cytokine-activated pri
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Martha Downen; Terry D. Amaral; Liwei L. Hua; Meng-Liang Zhao; Sunhee C. Lee
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Article
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1999
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John Wiley and Sons
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English
⚖ 696 KB
We examined cytokine-mediated neuronal death in neuron-astrocyte cultures from second trimester human fetal cerebrum. In these cultures, high-output inducible nitric oxide synthase (NOS) and tumor necrosis factor-␣ (TNF␣) are expressed in astrocytes after exposure to IL-1/IFN␥. Neuronal cell death