Tumor Necrosis Factor-α and Host Resistance to the Pathogenic Fungus, Histoplasma capsulatum
✍ Scribed by Deepe, George S
- Book ID
- 110050238
- Publisher
- Nature Publishing Group
- Year
- 2007
- Tongue
- English
- Weight
- 66 KB
- Volume
- 12
- Category
- Article
- ISSN
- 1087-0024
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Tumor necrosis factor a (TNF-a) is a cytokine with infectious agents and has been shown to exert direct pleiotropic properties that is induced in a variety of antiviral effects. [3][4][5] Although low levels of TNF-a can pathological situations including viral infections. In this contribute to cell
The sensitization of hepatocytes to cell death from tumor necrosis factor α (TNFα) underlies many forms of hepatic injury, including that from toxins. Critical for hepatocyte resistance to TNFα toxicity is activation of nuclear factor κB (NF-κB) signaling, which prevents TNFα-induced death by the up