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Tumor necrosis factor receptor–associated periodic syndrome: Toward a molecular understanding of the systemic autoinflammatory diseases

✍ Scribed by John G. Ryan; Ivona Aksentijevich


Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
41 KB
Volume
60
Category
Article
ISSN
0004-3591

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## Abstract ## Objective To investigate the effect of mutations in tumor necrosis factor receptor superfamily 1A (TNFRSF1A) on the ability of the receptors to be cleaved from the cell surface upon stimulation. The mutations we studied are associated with clinically distinct forms of TNF receptor–a