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Tumor necrosis factor receptor II gene polymorphism and severity of rheumatoid arthritis

✍ Scribed by Arnaud Constantin; Philippe Dieudé; Valérie Lauwers-Cancès; Bénédicte Jamard; Bernard Mazières; Anne Cambon-Thomsen; François Cornélis; Alain Cantagrel

Publisher: John Wiley and Sons
Year: 2004
Tongue: English
Weight: 67 KB
Volume: 50
Category: Article
ISSN: 0004-3591
DOI: 10.1002/art.20113

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## Abstract ## Objective To test whether the G‐to‐A polymorphism at position −308 in the promoter of the tumor necrosis factor α (TNFα) gene influences response to infliximab therapy in patients with rheumatoid arthritis (RA). ## Methods We genotyped 59 RA patients by polymerase chain reaction a