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Tumor necrosis factor receptor I from patients with tumor necrosis factor receptor–associated periodic syndrome interacts with wild-type tumor necrosis factor receptor I and induces ligand-independent NF-κB activation

✍ Scribed by Nasim Yousaf; David J. Gould; Ebun Aganna; Linda Hammond; Rita M. Mirakian; Mark D. Turner; Graham A. Hitman; Michael F. McDermott; Yuti Chernajovsky


Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
649 KB
Volume
52
Category
Article
ISSN
0004-3591

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## Abstract ## Objective To investigate the prevalence of tumor necrosis factor receptor–associated periodic syndrome (TRAPS) among outpatients presenting with recurrent fevers and clinical features consistent with TRAPS. ## Methods Mutational screening was performed in affected members of 18 fa