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Tumor Necrosis Factor Promotes Human T-Cell Development in Nonobese Diabetic/Severe Combined Immunodeficient Mice

โœ Scribed by Sarit Samira; Christophe Ferrand; Amnon Peled; Arnon Nagler; Yosef Tovbin; Herzl Ben-Hur; Naomi Taylor; Amiela Globerson; Tsvee Lapidot


Book ID
111846000
Publisher
AlphaMed Press
Year
2004
Tongue
English
Weight
592 KB
Volume
22
Category
Article
ISSN
1066-5099

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## Abstract Nonobese diabetic, severe combined immunodeficient (NOD/SCID) mice are extensively used to assess __in vivo__ potentials for human cellular differentiation, development, and neophysiology. They are not only deficient in T and B cells, but also exhibit macrophage dysfunction and an absen