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Tumor necrosis factor promoter polymorphism TNF*-857 is a risk allele for psoriatic arthritis independent of the PSORS1 locus

✍ Scribed by Emiliano Giardina; Ulrike Hüffmeier; Jaya Ravindran; Frank Behrens; Tiziana Lepre; Neil J. McHugh; Eleanor Korendowych; Harald Burkhardt; Giuseppe Novelli; André Reis

Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
69 KB
Volume
63
Category
Article
ISSN
0004-3591

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📜 SIMILAR VOLUMES

TNF polymorphisms in psoriasis: Associat
TNF polymorphisms in psoriasis: Association of psoriatic arthritis with the promoter polymorphism TNF*-857 independent of the PSORS1 risk allele
✍ Kristian Reich; Ulrike Hüffmeier; Inke R. König; Jesús Lascorz; Jörg Lohmann; Jö 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 94 KB 👁 1 views

## Abstract ## Objective Single‐nucleotide polymorphisms (SNPs) of the tumor necrosis factor gene __TNF__ at positions −238 and −308 have been associated with psoriasis vulgaris and psoriatic arthritis (PsA). The strong linkage disequilibrium (LD) at chromosome region 6p21, a region known to harbo