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Tumor necrosis factor alpha induced proliferation of adult neural stem cells is mediated via NF-κB

✍ Scribed by Darius Widera; Ilja Mikenberg; Margitta Elvers; Christian Kaltschmidt; Barbara Kaltschmidt


Book ID
115007230
Publisher
BioMed Central
Year
2007
Tongue
English
Weight
132 KB
Volume
8
Category
Article
ISSN
1471-2202

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## Abstract Resistance to tumor necrosis factor (TNFα)‐induced apoptosis in various cancer cells has been attributed to the activation of the transcription factor NF‐κB. Ebselen (2‐phenyl‐1,2‐benzisoselenazol‐3[2H]one)—a selenoorganic compound is known to prevent TNFα‐mediated NF‐κB activity. As gl