## Abstract There is growing evidence to suggest that not all cancer cells have similar levels of malignant potential and that tumor progression may be driven by specialized subβsets of βtumor initiatingβ cells. It is likely that as tumor initiating cells have lower proliferation rates and enhanced
Tumor initiating cells in malignant gliomas: biology and implications for therapy
β Scribed by Costas G. Hadjipanayis; Erwin G. Van Meir
- Publisher
- Springer
- Year
- 2009
- Tongue
- English
- Weight
- 382 KB
- Volume
- 87
- Category
- Article
- ISSN
- 0946-2716
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## BACKGROUND. The histologic differentiation of mitotic figures is a cornerstone of
## Abstract The capacity of adult human glial progenitor cells (AGPs), to proliferate and undergo multipotent differentiation, positions them as ideal candidate cells of origin for human gliomas. To investigate this potential role we identified AGPs as mitotically active Olig2 cells in nonneoplasti
## Abstract InterferonβΞ² (IFNβΞ²) has been used as an antitumor drug against human glioma, melanoma and medulloblastoma since the 1980s. Recently, we developed a new gene therapy using the __IFN__βΞ² gene against malignant gliomas and then began clinical trials in 2000. Since stimulation of immune sy