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Tumor-infiltrating T lymphocyte clonality predicts prognosis in human ovarian cancer

✍ Scribed by Takemasa Tsuji,Kevin H Eng,Sacha Gnjatic…

Book ID
126381358
Publisher
Springer (Biomed Central Ltd.)
Year
2013
Tongue
English
Weight
66 KB
Volume
1
Category
Article
ISSN
2051-1426

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## Abstract Seminoma lesions are characterized by a brisk inflammatory infiltrate containing both CD4 and CD8 T cells, which is of prognostic significance. However, whether seminoma cells express the HLA molecules required for classical T‐cell recognition remains controversial. In the present study