Tumor-infiltrating lymphocytes and hepatocellular carcinoma
โ Scribed by Yoshihiko Maehara
- Publisher
- Springer
- Year
- 2010
- Tongue
- English
- Weight
- 67 KB
- Volume
- 15
- Category
- Article
- ISSN
- 1341-9625
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๐ SIMILAR VOLUMES
We examined the clinicopathologic features of 11 surgically resected hepatocellular carcinomas (HCCs) less than 3 cm in diameter with marked inflammatory cell infiltration (LHCCs). In comparison with the other 152 HCCs without such an infiltration (controls), there were no significant differences in
Hepatocellular carcinoma (HCC) has a poor prognosis with limited therapeutic options. We propose that local immune responses in patients with HCC are held in check by tumor-infiltrating CD4(+)CD25(+) T-regulatory lymphocytes (T(reg) cells), which suppress the activity and proliferation of effector C