elevate plasma calcium by promoting bone resorption and decreasing calcium ria, Australia. excretion. Assays for plasma PTH-rP fail to detect protein convincingly in normal plasma, but measurable levels have been found in up to 100% of patients with HHM, in 75% of patients with breast carcinoma met
Tumor-induced hypercalcemia and parathyroid hormone-related protein in lung carcinoma
โ Scribed by Eiji Takai; Tokujiro Yano; Haruo Iguchi; Yasuro Fukuyama; Hideki Yokoyama; Hiroshi Asoh; Yukito Ichinose
- Publisher
- John Wiley and Sons
- Year
- 1996
- Tongue
- English
- Weight
- 318 KB
- Volume
- 78
- Category
- Article
- ISSN
- 0008-543X
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โฆ Synopsis
BACKGROUND.
Although lung carcinoma is the most common cause of tumorinduced hypercalcemia (TIH), the precise incidence of TIH remains obscure. Furthermore, the role of parathyroid hormone-related protein (PTHrP) has not been clearly elucidated.
๐ SIMILAR VOLUMES
Elevated levels of parathyroid hormone-related protein (PTHrP) in hypercalcemic myeloma patients were demonstrated in recent reports, suggesting that PTHrP behaves as a humoral mediator of hypercalcemia in myeloma. Herein we describe a hypercalcemic myeloma patient with a high serum PTHrP level. Mor