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Tumor growth pattern and thymidine phosphorylase expression are related with the risk of hematogenous metastasis in patients with Astler Coller B1/B2 colorectal carcinoma

✍ Scribed by Henk K. van Halteren; Herman M. Peters; J. Han J. M. van Krieken; Jan-Willem W. Coebergh; Rudi M. H. Roumen; Erik van der Worp; J. Theo Wagener; Gerard Vreugdenhil


Publisher
John Wiley and Sons
Year
2001
Tongue
English
Weight
191 KB
Volume
91
Category
Article
ISSN
0008-543X

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✦ Synopsis


BACKGROUND.

The benefit of adjuvant chemotherapy appears to be limited for patients with Astler Coller B1/B2 colorectal carcinoma but may be better in a subgroup of patients with a high recurrence risk. In the current case-control analysis, the authors evaluated whether patients with a high risk of hematogenous metastasis could be identified by means of a thorough histologic and immunohistochemical examination of the resection specimens.