Tumor factors predicting for prognosis in metastatic breast cancer: The presence of P24 predicts for response to treatment and duration of survival

Loss of heterozygosity proximal to the M

Loss of heterozygosity proximal to the M6P/IGF2R locus is predictive for the presence of disseminated tumor cells in the bone marrow of ovarian cancer patients before and after chemotherapy

✍ Jan Dominik Kuhlmann; Heidi Schwarzenbach; Friedrich Otterbach; Martin Heubner; 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 145 KB 👁 1 views

## Abstract Disseminated tumor cells (DTC) in the bone marrow (BM) are present in about 35% of ovarian cancers before surgery and after chemotherapy and are associated with worse prognosis. A molecular biomarker in the primary tumor predicting tumor cell spread would be highly desirable. The purpos