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Tumor exosomes expressing Fas ligand mediate CD8+ T-cell apoptosis

โœ Scribed by Ashraf J. Abusamra; Zhaohui Zhong; Xiufen Zheng; Mu Li; Thomas E. Ichim; Joseph L. Chin; Wei-Ping Min

Book ID
116304069
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
184 KB
Volume
35
Category
Article
ISSN
1079-9796

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## Thiols prevent Fas (CD95)-mediated T cell apoptosis by down-regulating membrane Fas expression Thiol antioxidants have been shown to protect cells against apoptosis. Based on the role of Fas in T cell apoptosis, we investigated the effect of thiols on Fas expression. We report that the thiol N-