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Tumor-Educated Macrophages Stimulate Tumor Progression in an Orthotopic Human Pancreatic Cancer Nude Mouse Model

✍ Scribed by R.S. Menen; M.K. Hassanein; M. Momiyama; A. Suetsugu; A.R. Moossa; R.M. Hoffman; M. Bouvet

Book ID: 116708184
Publisher: Elsevier Science
Year: 2012
Tongue: English
Weight: 44 KB
Volume: 172
Category: Article
ISSN: 0022-4804
DOI: 10.1016/j.jss.2011.11.360

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## Abstract Pancreatic adenocarcinoma has a rising incidence and a very poor survival rate. To develop new treatment strategies, extensive research is performed on animal models of pancreatic cancer. Orthotopic pancreatic tumors models, where the tumor is implanted into the pancreas, resemble the h