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Tumor-derived cytokines chemotactic for lymphokine-activated killer (LAK) and natural killer (NK) cells in vitro

✍ Scribed by He, Ya-fang; Chen, Hui-jin; Qian, Long-hua; He, Liu-fang; Buzby, Jeffrey S.


Book ID
122551145
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
164 KB
Volume
3
Category
Article
ISSN
1043-4666

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Adherent lymphokine-activated killer (A-LAK) cells are purified IL-2 activated natural killer (NK) cells with potent antitumor cytotoxic activity. They have been used in the adoptive immunotherapy of metastatic cancers. However, it has been shown that intravenously transferred IAK cells have a poor