## Abstract Both CTLA‐4 and TGF‐β have been implicated in suppression by CD4^+^CD25^+^ regulatory T cells (Treg). In this study, the relationship between CTLA‐4 and TGF‐β in Treg function was examined. Blocking CTLA‐4 on wild‐type Treg abrogated their suppressive activity __in vitro__, whereas neut
✦ LIBER ✦
Tumor-derived CD4+CD25+regulatory T cell suppression of dendritic cell function involves TGF-βand IL-10
✍ Scribed by Nicolas Larmonier; Marilyn Marron; Yi Zeng; Jessica Cantrell; Angela Romanoski; Marjan Sepassi; Sylvia Thompson; Xinchun Chen; Samita Andreansky; Emmanuel Katsanis
- Publisher
- Springer-Verlag
- Year
- 2006
- Tongue
- English
- Weight
- 460 KB
- Volume
- 56
- Category
- Article
- ISSN
- 0340-7004
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Distinct roles of CTLA-4 and TGF-β in CD
✍
Qizhi Tang; Elisa K. Boden; Kammi J. Henriksen; Helene Bour-Jordan; Mingying Bi;
📂
Article
📅
2004
🏛
John Wiley and Sons
🌐
English
⚖ 218 KB
Inhibition of CD40 expression and CD40-m
✍
Michael R. Shurin; Zoya R. Yurkovetsky; Irina L. Tourkova; Levent Balkir; Galina
📂
Article
📅
2002
🏛
John Wiley and Sons
🌐
French
⚖ 290 KB
As CD40 plays a key role in both antitumor immunity and DC maturation, we have studied the regulation of its expression during DC hematopoiesis (dendropoiesis) in vitro and in vivo in the tumor microenvironment. Using MC38 colon adenocarcinoma tumor models, we have demonstrated that DCs generated in
TGF-β1 production by CD4+CD25+ regulator
✍
Marika C. Kullberg; Valerie Hay; Allen W. Cheever; Mizuko Mamura; Alan Sher; Joh
📂
Article
📅
2005
🏛
John Wiley and Sons
🌐
English
⚖ 360 KB
Pertussis toxin as an adjuvant suppresse
✍
Xin Chen; Robin T. Winkler-Pickett; Nicholas H. Carbonetti; John R. Ortaldo; Joo
📂
Article
📅
2006
🏛
John Wiley and Sons
🌐
English
⚖ 353 KB
👁 1 views
Do activated human dendritic cells dimin
✍
Jagadeesh Bayry; Srini V. Kaveri; David F. Tough
📂
Article
📅
2007
🏛
John Wiley and Sons
🌐
English
⚖ 117 KB
👁 2 views
Deficient SOCS3 expression in CD4+CD25+F
✍
Brendan B. L. Pillemer; Hui Xu; Timothy B. Oriss; Zengbiao Qi; Anuradha Ray
📂
Article
📅
2007
🏛
John Wiley and Sons
🌐
English
⚖ 270 KB
👁 1 views