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Tumor-dependent activation of rodent hepatic stellate cells during experimental melanoma metastasis

✍ Scribed by E Olaso; A Santisteban; J Bidaurrazaga; AM Gressner; J Rosenbaum; F Vidal-Vanaclocha


Book ID
118686664
Publisher
John Wiley and Sons
Year
1997
Tongue
English
Weight
1003 KB
Volume
26
Category
Article
ISSN
0270-9139

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Tumor-dependent activation of rodent hep
✍ E Olaso; A Santisteban; J Bidaurrazaga; A M Gressner; J Rosenbaum; F Vidal-Vanac πŸ“‚ Article πŸ“… 1997 πŸ› John Wiley and Sons 🌐 English βš– 1004 KB

In this work we report the presence of intrametastatic smooth-muscle iso-alpha-actin (SMA)-expressing cells which appeared from the early stages of the hepatic metastasis process of intrasplenically injected B16 melanoma (B16M) cells. They formed a network of stromal cells among B16M cells, a very l

Activated hepatic stellate cells induce
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## Abstract The development of hepatocellular carcinomas from malignant hepatocytes is frequently associated with intra‐ and peritumoral accumulation of connective tissue arising from activated hepatic stellate cells. For both tumorigenesis and hepatic fibrogenesis, transforming growth factor (TGF)