Tirapazamine, a new bioreductive agent currently advancing through clinical trials, may have a valuable role to play in cancer therapy. In vitro, the drug shows markedly more toxicity to hypoxic cells than to aerobic cells, and preferential activity against hypoxic cells of solid tumors in vivo also
Tumor cytokinetic effects of acute starvation versus polyamine depletion in tumor-bearing mice
✍ Scribed by Thomas Westin; Bertil Gustafsson; Karin Hellander; Lola Reinholdtsen; Lena Tibell; Kent Lundholm; Staffan Edström
- Publisher
- John Wiley and Sons
- Year
- 1991
- Tongue
- English
- Weight
- 826 KB
- Volume
- 12
- Category
- Article
- ISSN
- 0196-4763
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