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Tumor cells heterogeneity and mechanism of action of antimetastatic drugs

โœ Scribed by S. Zorzet; T. Giraldi; G. Sava; L. Perissin; P. Piccini; S. Pacor; V. Rapozzi


Book ID
114075827
Publisher
Elsevier Science
Year
1988
Weight
77 KB
Volume
20
Category
Article
ISSN
0031-6989

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The antimetastatic effects of heparin (40 units) and prostacyclin (PGI2, 100 microgram)1 were investigated in normal mice and in mice with depressed or activated natural killer (NK) cell activity. Both anticoagulants inhibited the formation of lung metastases after inoculation of the FI or F10 subli