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Tumor Budding and Pathological Differentiation Are Predictive Markers for Lymph Node Metastasis in T1 Colorectal Cancer

✍ Scribed by Hitoshi Yamauchi; Kazutomo Togashi; Hiroshi Kawamura; Junichi Sasaki; Masaki Okada; Fumio Konishi

Book ID
119242986
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
49 KB
Volume
63
Category
Article
ISSN
1097-6779

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## Abstract ## Purpose Chromosome 18q21 deletion and Smad4 protein inactivation have been reported as molecular markers predicting unfavorable outcome in colorectal cancers and, in a previous report, we recently revealed that these molecules are closely associated with distant metastasis, which is