Tumor blood flow changes induced by chemical modifiers of radiation response
β Scribed by David J. Chaplin; Michael R. Horsman
- Publisher
- Elsevier Science
- Year
- 1992
- Tongue
- English
- Weight
- 472 KB
- Volume
- 22
- Category
- Article
- ISSN
- 0360-3016
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Tumor metabolism is directly coupled to tumor blood flow (TBF) and both metabolism and blood flow may be determinants of tumor response to treatment. Since NMR has been used extensively to monitor tumor metabolism noninvasively, development of NMR-based methods for TBF measurement was motivated by t
## Abstract Perfusion plays a key role in tumor proliferation and therapeutic response. Tumor heterogeneity necessitates use of the highest spatial resolution to monitor metabolic correlates of blood flow changes. This is best achieved with ^1^H NMR spectroscopy, which permits noninvasive acquisiti