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Tumor-associated osteoclast activity and aggressiveness of osteosarcoma

โœ Scribed by Sofia Avnet; Alessandra Longhi; Manuela Salerno; Jussi Halleen; Francesca Perut; Donatella Granchi; Armando Giunti; Nicola Baldini

Book ID
116320539
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
70 KB
Volume
42
Category
Article
ISSN
8756-3282

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The cellular and biochemical mechanisms that direct destruction of bone at the site of tumor osteolysis are unknown. In order to understand this process better, a murine model designed for the study of tumor osteolysis was developed and the influence of osteolytic and nonosteolytic tumors on bone wa