✦ LIBER ✦
Tumor-associated antigen TA-90 immune complex assay predicts subclinical metastasis and survival for patients with early stage melanoma
✍ Scribed by Mark C. Kelley; Ralph C. Jones; Rishab K. Gupta; Reynold Yee; Stacey Stern; Leslie Wanek; Donald L. Morton
- Book ID
- 101230876
- Publisher
- John Wiley and Sons
- Year
- 1998
- Tongue
- English
- Weight
- 105 KB
- Volume
- 83
- Category
- Article
- ISSN
- 0008-543X
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✦ Synopsis
BACKGROUND.
TA-90 is a tumor-associated antigen first identified in the urine and sera of patients with metastatic melanoma. In the early stages of disease, TA-90 is present in circulating immune complexes (ICs) that may be detected with an antigen specific enzyme-linked immunosorbent assay (ELISA). In this study, the authors evaluated the efficacy of the TA-90 IC assay in detecting subclinical metastasis of early stage melanoma and predicting the survival of patients with this disease.