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Tumor Antigens Recognized by T Lymphocytes

โœ Scribed by Boon, Thierry; Cerottini, Jean-Charles; Van den Eynde, Benoit; van der Bruggen, Pierre; Van Pel, Aline


Book ID
117992509
Publisher
Annual Reviews
Year
1994
Tongue
English
Weight
764 KB
Volume
12
Category
Article
ISSN
0732-0582

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Molecular definition of tumor antigens r
โœ Pierre van der Bruggen; Benoit Van den Eynde ๐Ÿ“‚ Article ๐Ÿ“… 1992 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 726 KB

Several tumor antigens recognized by T cells have now been identified at the molecular level. Various mechanisms can account for their expression: activation of normally silent genes; point mutations; chromosome translocations; and post-translational modifications of proteins. This led to the notion