## Abstract Spontaneous tumors frequently express antigens that can be recognized by the immune system but nevertheless manage to evade immune surveillance. To better understand the mechanism of evasion, we followed CD8 and CD4 T cells reacting against a subcutaneously growing tumor, modified to ex
β¦ LIBER β¦
Tumor antigen-specific CD4 + T cells in cancer immunity: from antigen identification to tumor prognosis and development of therapeutic strategies
β Scribed by Protti, M. P.; Monte, L. D.; Lullo, G. D.
- Book ID
- 127052150
- Publisher
- John Wiley and Sons
- Year
- 2014
- Tongue
- English
- Weight
- 736 KB
- Volume
- 83
- Category
- Article
- ISSN
- 0001-2815
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## Abstract Evidence is presented for specific in vitro killing of neoplastic target cells in the presence of nonβsensitized lymphoid cells and heat decomplemented sera from mice bearing the respective neoplasms or whose tumors had been removed. Such an effect was observed with sera from mice beari