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Tubulin Binding Sites on γ-Tubulin: Identification and Molecular Characterization †

✍ Scribed by Llanos, Roxana; Chevrier, Véronique; Ronjat, Michel; Meurer-Grob, Patricia; Martinez, Pascal; Frank, Ronald; Bornens, Michel; Wade, Richard H.; Wehland, Juergen; Job, Didier


Book ID
121232538
Publisher
American Chemical Society
Year
1999
Tongue
English
Weight
767 KB
Volume
38
Category
Article
ISSN
0006-2960

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## Abstract Tubulin is an attractive and established target for anticancer therapy. To date, the only method to determine the binding of inhibitor to tubulin has been competitive radioligand binding assays. We developed a non‐radioactive mass spectrometry (MS) binding assay to study the tubulin bin