✦ LIBER ✦

Tubulin and FtsZ structures: functional and therapeutic implications

✍ Scribed by Arshad Desai; Timothy J. Mitchison

Publisher: John Wiley and Sons
Year: 1998
Tongue: English
Weight: 200 KB
Volume: 20
Category: Article
ISSN: 0265-9247
DOI: 10.1002/(sici)1521-1878(199807)20:7<523::aid-bies1>3.0.co;2-l

No coin nor oath required. For personal study only.

✦ Synopsis

The microtubule cytoskeleton has lagged nearly a decade behind the actin cytoskeleton with respect to structural information on the basic polymer subunit. This structural inferiority complex has finally been lifted by two recent papers describing the structures of the ␣␤ tubulin dimer (1) and FtsZ, (2) a protein similar to tubulin that is essential for cell division in prokaryotes.

📜 SIMILAR VOLUMES

Nuclear structure and function

✍ Gary S. Stein; Ronald Berezney 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 190 KB 👁 1 views

A new functional classification of tumor

A new functional classification of tumor-suppressing genes and its therapeutic implications

✍ M. Quamrul Islam; Khaleda Islam 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 219 KB 👁 1 views

Cell fusion studies have demonstrated that malignancy can be suppressed by a single dose of malignancy suppressor genes (MSGs), indicating that malignancy is a recessive phenotype. Correspondingly, it is widely believed that mutational inactivation of both alleles of tumor suppressor genes (TSGs), i

Changes in sub-nuclear structures and fu

Changes in sub-nuclear structures and functional perturbations: Implications for radiotherapy

✍ J.L. Roti Roti; D. Gius; R.P. VanderWaal; M. Xu 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 224 KB

Nucleosome and chromatin structures and

Nucleosome and chromatin structures and functions

✍ E. Morton Bradbury 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 63 KB 👁 1 views

Gynecomastia in testicular cancer patien

Gynecomastia in testicular cancer patients prognostic and therapeutic implications

✍ Alexander Tseng JR; Sandra J. Horning; Fuad S. Freiha; Kenneth J. Resser; John F 📂 Article 📅 1985 🏛 John Wiley and Sons 🌐 English ⚖ 441 KB

Eighty-one patients with advanced testicular cancer were evaluated for gynecomastia or severe breast tenderness at diagnosis and after platinum-based chemotherapy. The prognostic significance of gynecomastia in these two settings was explored. At presentation, 10% (8 patients) had gynecomastia or br

Systems engineering: Purpose, function,

Systems engineering: Purpose, function, and structure

✍ Andrew P. Sage 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 86 KB 👁 1 views

Systems Engineering is the new quarterly archival journal of the International Council on Systems Engineering (INCOSE). It is a fully refereed journal and a primary source of multidisciplinary information for the system engineering and management of products and services, and processes of all types.