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Tu2033 Role of Methionine Adenosyltransferase 2β in Resveratrol's Biological Activities in Liver Cancer Cells

✍ Scribed by Yang, Heping; Zheng, Yuhua; Rojas, Adriana L.; Mato, Jose M.; Lu, Shelly C.

Book ID
122525645
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
49 KB
Volume
144
Category
Article
ISSN
0016-5085

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Leptin's mitogenic effect in human liver
Leptin's mitogenic effect in human liver cancer cells requires induction of both methionine adenosyltransferase 2A and 2β
✍ Komal Ramani; Heping Yang; Meng Xia; Ainhoa Iglesias Ara; José M. Mato; Shelly C 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 698 KB

Leptin is an adiopokine that plays a pivotal role in the progression of liver fibrogenesis and carcinogenesis. Recently, leptin was shown to be mitogenic in human liver cancer cell lines HepG2 and Huh7. Whether leptin can act as a mitogen in normal hepatocytes is unclear. Methionine adenosyltransfer