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Tu1923 The Effect of Antigen Oxidation and TGF on NaïVE T Cell Phenotype and Proliferation

✍ Scribed by Khanna, Sahil; Tremaine, William I.; Dave, Maneesh; Svingen, Phyllis A.; Xiong, Yuning; Linden, David R.; Faubion, William A.


Book ID
122104134
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
65 KB
Volume
142
Category
Article
ISSN
0016-5085

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The role of TGF-g 1 in the regulation of T cell responses has been perplexing, possibly because it is dependent on the type of T cell being regulated and its cytokine microenvironment. In the present study, we demonstrate that TGF-g 1 has a profound inhibitory effect on naive CD4 + T cell undergoing