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Tu1686 Attenuation of Pancreatic Cancer Cell Migration and Invasion Through a Targeted Inhibition of the Rac GEF Vav1

โœ Scribed by Razidlo, Gina L.; Magnine, Christopher; Sletten, Arthur C.; Hurley, Rachel M.; McNiven, Mark A.

Book ID
122216620
Publisher
Elsevier Science
Year
2014
Tongue
English
Weight
254 KB
Volume
146
Category
Article
ISSN
0016-5085

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## Abstract Pancreatic cancer is a highly aggressive malignancy and one of the leading causes of cancer deaths, mainly due to the lack of methods for early diagnosis and the lack of effective therapies. Recent CGH microarray studies have revealed several regions that are recurrently amplified in pa